Entrez 6793 | Ensembl ENSG00000072786 | |
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External IDs MGI: 1099439 HomoloGene: 38122 GeneCards: STK10 |
Serine/threonine-protein kinase 10 is an enzyme that in humans is encoded by the STK10 gene.
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.
References
STK10 Wikipedia(Text) CC BY-SA