SPTBN5

Updated on Dec 27, 2024

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Species Human Entrez 51332		Human Mouse Ensembl ENSG00000137877
Aliases SPTBN5, BSPECV, HUBSPECV, HUSPECV, spectrin beta, non-erythrocytic 5 External IDs MGI: 2685200 HomoloGene: 41150 GeneCards: SPTBN5

Spectrin, beta, non-erythrocytic 5 also known as SPTBN5 is a protein that in humans is encoded by the SPTBN5 gene. SPTBN5 belongs to the spectrin family of cytoskeletal proteins.

Structure and function

SPTBN5 contains the following domains:

actin-binding domain

membrane-association domain-1

self-association domain

C-terminal pleckstrin homology domain.

Based on these structural features it is thought that SPTBN5 is likely to form heterodimers and oligomers with alpha-spectrin and to interact directly with cellular membranes.

SPTBN5 is highly expressed in embryoid bodies.

References

SPTBN5 Wikipedia

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