Suvarna Garge (Editor)

SPTBN5

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Species
  
Human

Entrez
  
51332

Human
  
Mouse

Ensembl
  
ENSG00000137877

Aliases
  
SPTBN5, BSPECV, HUBSPECV, HUSPECV, spectrin beta, non-erythrocytic 5

External IDs
  
MGI: 2685200 HomoloGene: 41150 GeneCards: SPTBN5

Spectrin, beta, non-erythrocytic 5 also known as SPTBN5 is a protein that in humans is encoded by the SPTBN5 gene. SPTBN5 belongs to the spectrin family of cytoskeletal proteins.

Structure and function

SPTBN5 contains the following domains:

  • actin-binding domain
  • membrane-association domain-1
  • self-association domain
  • C-terminal pleckstrin homology domain.

    • Based on these structural features it is thought that SPTBN5 is likely to form heterodimers and oligomers with alpha-spectrin and to interact directly with cellular membranes.

    SPTBN5 is highly expressed in embryoid bodies.

    References

    SPTBN5 Wikipedia
    (Text) CC BY-SA