Species Human Entrez 25803 | Human Mouse Ensembl ENSG00000124664 | |
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Aliases SPDEF, PDEF, bA375E1.3, SAM pointed domain containing ETS transcription factor External IDs MGI: 1353422 HomoloGene: 8231 GeneCards: SPDEF | ||
SAM pointed domain-containing Ets transcription factor is a protein that in humans is encoded by the SPDEF gene.
PDEF is an ETS transcription factor expressed in prostate epithelial cells. It acts as an androgen-independent transactivator of PSA (MIM 176820) expression.[supplied by OMIM]
Interactions
SPDEF has been shown to interact with NKX3-1.
The Protein Kinase CK2 has been shown to control the stability of PDEF.
References
SPDEF Wikipedia(Text) CC BY-SA