Species Human Entrez 9580 | Human Mouse Ensembl ENSG00000143842 | |
 | ||
Aliases SOX13, ICA12, Sox-13, SRY-box 13 External IDs MGI: 98361 HomoloGene: 4159 GeneCards: SOX13 | ||
Transcription factor SOX-13 is a protein that in humans is encoded by the SOX13 gene.
Function
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12.
In melanocytic cells SOX13 gene expression may be regulated by MITF.
References
SOX13 Wikipedia(Text) CC BY-SA