Puneet Varma (Editor)

SOX13

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Species
  
Entrez
  
9580

Human
  
Ensembl
  
ENSG00000143842

SOX13

Aliases
  
SOX13, ICA12, Sox-13, SRY-box 13

External IDs
  
MGI: 98361 HomoloGene: 4159 GeneCards: SOX13

Transcription factor SOX-13 is a protein that in humans is encoded by the SOX13 gene.

Function

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12.

In melanocytic cells SOX13 gene expression may be regulated by MITF.

References

SOX13 Wikipedia


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