Species Human Entrez 25928 | Human Mouse Ensembl ENSG00000171243 | |
 | ||
Aliases SOSTDC1, ECTODIN, USAG1, CDA019, DAND7, sclerostin domain containing 1 External IDs MGI: 1913292 HomoloGene: 9154 GeneCards: SOSTDC1 | ||
Sclerostin domain-containing protein 1 is a protein that in humans is encoded by the SOSTDC1 gene.
Function
This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.
References
SOSTDC1 Wikipedia(Text) CC BY-SA