EC number 1.5.3.16 | Entrez 54498 | |
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Aliases SMOX, C20orf16, PAO, PAO-1, PAO1, PAOH, PAOH1, SMO, spermine oxidase External IDs MGI: 2445356 HomoloGene: 69268 GeneCards: SMOX |
Function
The product of this gene is the polyamine oxidase. This enzyme potentially represents a new class of catabolic enzymes in the mammalian polyamine metabolic pathway capable of the efficient oxidation of polyamines. More than five transcript variants encoding four active isoenzymes have been identified for this gene, however, not all variants have been fully described. The characterized isoenzymes have distinctive biochemical characteristics and substrate specificities, suggesting the existence of additional levels of complexity in polyamine catabolism.
References
SMOX Wikipedia(Text) CC BY-SA