Species Human Entrez 57152 | Human Mouse Ensembl ENSG00000126233 | |
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Aliases SLURP1, ANUP, ARS, ArsB, LY6LS, MDM, secreted LY6/PLAUR domain containing 1 External IDs MGI: 1930923 HomoloGene: 10710 GeneCards: SLURP1 | ||
Secreted Ly-6/uPAR-related protein 1 is a protein that in humans is encoded by the SLURP1 gene.
Function
The protein encoded by this gene is a member of the Ly6/uPAR family but lacks a GPI-anchoring signal sequence. It is thought that this secreted protein contains antitumor activity. Mutations in this gene have been associated with Mal de Meleda, a rare autosomal recessive skin disorder. This gene maps to the same chromosomal region as several members of the Ly6/uPAR family of glycoprotein receptors.
References
SLURP1 Wikipedia(Text) CC BY-SA