Species Human Entrez 54946 | Human Mouse Ensembl ENSG00000114544 | |
Aliases SLC41A3, SLC41A1-L2, solute carrier family 41 member 3 External IDs MGI: 1918949 HomoloGene: 23052 GeneCards: SLC41A3 | ||
Solute carrier family 41, member 3 is a protein that in humans is encoded by the SLC41A3 gene.
Model organisms
Model organisms have been used in the study of SLC41A3 function. A conditional knockout mouse line, called Slc41a3tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty six tests were carried out on mutant mice and one significant abnormality was observed: homozygous mutants displayed abnormal locomotor coordination.
References
SLC41A3 Wikipedia(Text) CC BY-SA