Species Human Entrez 6580 | Human Mouse Ensembl ENSG00000175003 | |
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Aliases SLC22A1, HOCT1, OCT1, oct1_cds, solute carrier family 22 member 1 External IDs MGI: 108111 HomoloGene: 20665 GeneCards: SLC22A1 | ||
Solute carrier family 22 member 1 is a protein that in humans is encoded by the SLC22A1 gene.
Function
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter.
References
SLC22A1 Wikipedia(Text) CC BY-SA