Entrez 57823 | Ensembl ENSG00000026751 | |
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Aliases SLAMF7, 19A, CD319, CRACC, CS1, SLAM family member 7 External IDs MGI: 1922595 HomoloGene: 49660 GeneCards: SLAMF7 | ||
Gene music using protein sequence of slamf7 slam family member 7
SLAM family member 7 is a protein that in humans is encoded by the SLAMF7 gene.
The surface antigen CD319 (SLAMF7) is a robust marker of normal plasma cells and malignant plasma cells in multiple myeloma. In contrast to CD138 (the traditional plasma cell marker), CD319/SLAMF7 is much more stable and allows robust isolation of malignant plasma cells from delayed or even cryopreserved samples.
Elotuzumab is an antibody that targets this protein.
References
SLAMF7 Wikipedia(Text) CC BY-SA