Rahul Sharma (Editor)

SIB 1757

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CAS Number
  
31993-01-8

ChemSpider
  
10654582

Formula
  
C12H11N3O

Molar mass
  
213.235 g/mol

PubChem CID
  
6849066

ECHA InfoCard
  
100.164.315

3D model (Jmol)
  
Interactive image

SIB-1757 httpsuploadwikimediaorgwikipediacommonsthu

SIB-1757 is a drug used in scientific research which was one of the first compounds developed that acts as a selective antagonist for the metabotropic glutamate receptor subtype mGluR5. It has anti-hyperalgesia effects in animals. SIB-1757 along with other mGluR5 antagonists has been shown to have neuroprotective and hepatoprotective effects, and it is also used to study the role of the mGluR5 receptor in brain development.

References

SIB-1757 Wikipedia