Kalpana Kalpana (Editor)

SB 408124

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CAS Number
  
288150-92-5

IUPHAR/BPS
  
1704

ECHA InfoCard
  
100.164.461

Molar mass
  
356.368 g/mol

PubChem CID
  
4331799

ChemSpider
  
3536200

Formula
  
C19H18F2N4O

SB-408124 httpsuploadwikimediaorgwikipediacommonsthu

SB-408124 is a drug which is a non-peptide antagonist selective for the orexin receptor subtype OX1, with around 70x selectivity for OX1 over OX2 receptors, and improved oral bioavailability compared to the older OX1 antagonist SB-334867. It is used in scientific research into the function of orexinergic neurons in the body.

References

SB-408124 Wikipedia