EC number 3.4.22.69 BRENDA BRENDA entry KEGG KEGG entry | IntEnz IntEnz view ExPASy NiceZyme view MetaCyc | |
SARS coronavirus main proteinase (EC 3.4.22.69, 3cLpro, 3C-like protease, coronavirus 3C-like protease, Mpro, SARS 3C-like protease, SARS coronavirus 3CL protease, SARS coronavirus main peptidase, SARS coronavirus main protease, SARS-CoV 3CLpro enzyme, SARS-CoV main protease, SARS-CoV Mpro, severe acute respiratory syndrome coronavirus main protease) is an enzyme. This enzyme catalyses the following chemical reaction
TSAVLQ-SGFRK-NH2 and SGVTFQ-!GKFKK are the two peptides corresponding to the two self-cleavage sites of the SARS 3C-like proteinase
This protease is important in SARS coronavirus replicase polyprotein processing.
References
SARS coronavirus main proteinase Wikipedia(Text) CC BY-SA