S specific spore photoproduct lyase

S-specific spore photoproduct lyase (EC 4.1.99.15, SAM, SP lyase, SPL, SplB, SplG) is an enzyme with systematic name S-specific spore photoproduct pyrimidine-lyase. This enzyme catalyses the following chemical reaction

(5S)-5,6-dihydro-5-(thymidin-7-yl)thymidine (in DNA) + S-adenosyl-L-methionine ⇌ thymidylyl-(3'->5')-thymidylate (in DNA) + 5'-deoxyadenosine + L-methionine

This enzyme is an iron-sulfur protein.