S methyl 5' thioinosine phosphorylase

S-methyl-5'-thioinosine phosphorylase (EC 2.4.2.44, MTIP, MTI phosphorylase, methylthioinosine phosphorylase) is an enzyme with systematic name S-methyl-5'-thioinosine:phosphate S-methyl-5-thio-alpha-D-ribosyl-transferase. This enzyme catalyses the following chemical reaction

S-methyl-5'-thioinosine + phosphate ⇌ hypoxanthine + S-methyl-5-thio-alpha-D-ribose 1-phosphate

The catabolism of 5'-methylthioadenosine in Pseudomonas aeruginosa involves deamination to S-methyl-5'-thioinosine (EC 3.5.4.31, S-methyl-5'-thioadenosine deaminase) and phosphorolysis to hypoxanthine.