Söderström is a surname of Swedish origin, and Søderstrøm a surname of Norwegian origin. Both mean "south stream; or, river"; and both are commonly anglicized as Soderstrom. People with those surnames include:
Bruno Söderström (1881–1969), Swedish track and field athleteChristian Söderström (born 1980), Swedish ice hockey playerDan Söderström (born 1948), Swedish ice hockey playerElisabeth Söderström (1927–2009), Swedish soprano noted for her performances of both opera and songFredrik Söderström (born 1973), Swedish footballerGustaf Söderström (1865–1958), Swedish athlete who won a gold medal at the 1900 Olympic GamesJonatan Söderström (AKA "Cactus", active from 2008), Swedish independent video game developerMarit Söderström (born 1962), Swedish sailor who competed in the 1988 Summer OlympicsPer Søderstrøm (born 1943), Norwegian handball player who competed in the 1972 Summer OlympicsReuben G. Soderstrom (1888–1970), American labor union leader in IllinoisSteve Soderstrom (born 1972), American baseball playerThomas Robert Soderstrom (1936–87), American agrostologistTim Söderström (born 1994), Swedish footballerTommy Söderström (born 1969), Swedish ice hockey goaltenderUlf Söderström (born 1972), Swedish ice hockey playerVictor Söderström (born 1994), Swedish footballer