Rye is a surname. Notable people with the surname include:
Daphne Rye (1916–1992), English theatre actress and director
Maria Rye (1829–1903), English social reformer
Michael Rye (born 1918), American voice actor
Olaf Rye (1791–1849), Dano-Norwegian military officer
Roger Rye, MP for Kent
Stellan Rye (1880–1914), Danish-born film director
Thomas Clark Rye (1863–1953), American politician