Rupe is a masculine given name, often a diminutive form (hypocorism) of Rupert. People named Rupe include:
Rupert Rupe Andrews (1926-2008), American player in the Canadian Football League
Rupe Benstead (1889–1961), Australian rules footballer
Rupe Bethune (1917–1984), Australian rules footballer
Rupe Brownlees (1888–1960), Australian rules footballer
Rupe Dodd (1907–1998), Australian rules footballer
Rupe Hannah (1900-1983), Australian rules footballer
Rupert Rupe Hiskins (1893–1976), Australian rules footballer
Rupe Hutton (1906–1987), Australian rules footballer
Rupe Lowell (1893–1980), Australian rules footballer
Rupe McDonald (1910–1969), Australian rules footballer
Rupe Perrett (1909-1966), Australian rules footballer
Rupert Smith (American football) (1897-1959), American college football player
