Routes of
administration Oral Bioavailability 80–90% Biological half-life 5–7 hours CAS ID 78628-28-1 | ATC code A02BA06 (WHO) Protein binding 5–7% Molar mass 348.437 g/mol | |
Metabolism | ||
Roxatidine acetate is a specific and competitive histamine H2 receptor antagonist drug that is used to treat gastric ulcers, Zollinger–Ellison syndrome, erosive esophagitis, gastro-oesophageal reflux disease, and gastritis.
Pharmacodynamic studies showed that 150 mg of roxatidine acetate were optimal in suppressing gastric acid secretion, and that a single bedtime dose of 150 mg was more effective than a dose of 75 mg twice daily in terms of inhibiting nocturnal acid secretion.
It is available in countries including China, Japan, Korea, Germany, Italy, the Netherlands, Greece and South Africa.
References
Roxatidine acetate Wikipedia(Text) CC BY-SA