Rosabelle Osborne, CBE, RRC (died 8 May 1958) was Principal Matron at the British War Office, 1924. She advanced and served as Matron-in-Chief at the QAIMNS (Queen Alexandra's Imperial Military Nursing Service) from 1 April 1928 until 1930.
The second daughter of Dr. J. A. Osborne of Milford, County Donegal, Rosabelle Osborne received her training at the Manchester Children's Hospital, Pendlebury, and Bristol Royal Infirmary. She served with the QAIMNS from May 1903. She was on active service during World War I abroad, in France, Egypt, Malta and Salonika.