Rispoli is a surname. Notable persons with that surname include:
Andrea Rispoli (born 1988), Italian footballer
Giovanni Rispoli (1836–?), Italian engraver
Giuseppe Checchia Rispoli (1877–1947), Italian geologist and paleontologist
James Rispoli, former Assistant Secretary of Energy for Environmental Management
John Matthew Rispoli (1582–1639), Maltese philosopher
Luciano Rispoli (1932–2016), Italian journalist
Michael Rispoli (born 1960), American actor
Umberto Rispoli, Italian horse racing jockey
