EC number 2.7.1.5 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9030-52-8 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a rhamnulokinase (EC 2.7.1.5) is an enzyme that catalyzes the chemical reaction
ATP + L-rhamnuloseThus, the two substrates of this enzyme are ATP and L-rhamnulose, whereas its two products are ADP and L-rhamnulose 1-phosphate.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:L-rhamnulose 1-phosphotransferase. Other names in common use include RhuK, rhamnulokinase (phosphorylating), L-rhamnulokinase, L-rhamnulose kinase, and rhamnulose kinase. This enzyme participates in pentose and glucuronate interconversions and fructose and mannose metabolism.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes by Grueninger and Schulz with PDB accession codes 2CGJ, 2CGK, 2CGL, and 2UYT.