Regis or Régis is a given name. Notable persons with that surname include:
Régis Amarante Lima de Quadros (born 1976), Brazilian association football player
Regis J. Armstrong, American Roman Catholic priest and professor
Régis Avila (born 1962), Brazilian fencer
Régis Barailla (1933-2016), French politician
Régis Blachère, French orientalist
Régis Bonissent (born 1948), French fencer
Regis Brodie (born 1942), American Professor of Art and potter
Régis Brouard (born 1967), French association football player
Régis Campo (born 1968), French composer
Regis Canevin (1853–1927), American Roman Catholic prelate
Regis Chakabva (born 1987), Zimbabwean cricketer
Régis Clère (born 1956), French road bicycle racer
Regis Cordic (1926–1999), American radio personality and actor
Régis Debray (born 1941), French intellectual, journalist and politician
Régis Delépine (born 1946), French road bicycle racer
Régis Dericquebourg (born 1947), French sociologist
Régis de l'Estourbeillon (1858–1946), French aristocrat and politician
Régis de Oliveira (born 1944), Brazilian politician
Regis de Souza (born 1982), Brazilian association footballer
Régis de Trobriand (1816–1897), French aristocrat, lawyer, poet and novelist
Régis Dorn (born 1979), French association football player
Regis Felisberto Masarim (born 1973), Brazilian football player
Regis Fernandes Silva (born 1976), Brazilian association football player
Régis Fuchs (born 1970), Swiss ice hockey winger
Régis Genaux (1973–2008), Belgian association football player
Régis Ghesquière (born 1949), Belgian decathlete
Regis Ghezelbash (born 1951), Iranian-French film director
Régis Gurtner (born 1986), French association football player
Régis François Gignoux (1816–1882), French painter
Régis Gizavo, Malagasy accordionist
Regis Gurtner (born 1986), French football goalkeeper
Régis Jauffret, French writer
Régis Jolivet (1891–1966), French philosopher and Roman Catholic priest
Régis Juanico (born 1972), member of the National Assembly of France
Regis B. Kelly, Scottish neuroscientist and university administrator
Regis "Pep" Kelly (1914–1990), Canadian ice hockey player
Régis Kittler (born 1979), French football player
Régis Koundjia (born 1983), former Central African Republic basketball player
Régis Labeaume (born 1956), Canadian businessman and writer
Régis Laconi (born 1975), French motorcycle racer
Régis Laguesse (born 1950), French association football player and coach
Régis Laspalès (born 1957), French comedian and actor
Régis Le Sommier (born 1969), French journalist
Regis Leheny (1908–1976), American baseball pitcher
Régis Loisel (born 1951), French comics writer and artist
Regis Malady (1917–1985), American politician from Pennsylvania
Regis McKenna, American marketing entrepreneur
Régis Messac (1893–1945), French writer
Regis Monahan (born 1908), American football player
Regis Philbin (born 1931), American television personality
Regis Pitbull (born 1976), Brazilian association football player
Regis Henri Post (1870–1944), New York politician and Governor of Puerto Rico
Régis Racine (born 1970), French basketball player
Régis Rey (born 1929), French ski jumper
Régis Rothenbühler (born 1970), Swiss association football player
Régis Schleicher (born 1957), French anarchist
Régis Sénac, French fencer and instructor
Régis Simon (born 1958), French road bicycle racer
Regis Toomey (1898–1991), American actor
Régis Wargnier (born 1948), French film director, producer, screenwriter, actor and film score composer
