Rauwolscine

Rauwolscine, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an alkaloid found in various species within the genera Rauwolfia and Pausinystalia (formerly known as Corynanthe). It is a stereoisomer of yohimbine. Rauwolscine is a central nervous system stimulant, a local anesthetic and a vague aphrodisiac.

Rauwolscine acts predominantly as a α₂-adrenergic receptor antagonist. It has also been shown to function as a 5-HT_1A receptor partial agonist and 5-HT_2A and 5-HT_2B receptor antagonist.