Randle, as a surname or a given name, may refer to:
Surname:
Betsy Randle (born 1955), American actress
Bill Randle (1923-2004), American disc jockey, lawyer and university professor
Brian Randle (born 1985), American basketball player in the Israeli Basketball Super League
Chasson Randle (born 1993), American college basketball player
Ervin Randle (born 1962), National Football League linebacker and brother of John Randle
Florence Randle, American photographer
Frank Randle (1901-1957), English comedian
Harry Randle (1906-1976), English footballer
Ian Randle (born 1940), Jamaican publisher
Jack Randle (1902-1990), English footballer
Jerome Randle (born 1987), American college and professional basketball player
John Randle (born 1967), retired National Football League defensive tackle and member of the Pro Football Hall of Fame
John K. Randle (1855–1928), West African doctor active in politics in Lagos, now in Nigeria, in the colonial era.
John Niel Randle (1917-1944), British captain and posthumous recipient of the Victoria Cross
Joseph Randle (born 1991), National Football League running back
Julius Randle (born 1994), American basketball player
Kevin D. Randle (born 1949), ufologist
Lenny Randle (born 1949), retired Major League Baseball player
Lynda Randle, African American singer of southern gospel
Mary Jo Randle, English actress
Michael Randle (born 1933), British peace activist who helped the Soviet spy George Blake escape from prison
Philip Randle (1926–2006), medical researcher
Rodger Randle, American politician from the 1970s on
Roger Randle (born 1974), New Zealand rugby union footballer
Rueben Randle (born 1991), National Football League wide receiver
Sonny Randle (born 1936), sportscaster and former National Football League player and college coach
Tate Randle (born 1959), retired National Football League cornerback
Theresa Randle (born 1964), American actress
Valerie Randle, Welsh materials engineer and professor at Swansea University
Vicki Randle (born 1954), American singer, musician and composer; first and only female member of The Tonight Show Band
Given name:
Randle Ayrton (1869–1940), British actor, producer and director
Randle Chowning (born 1950), American singer-songwriter best known as the founder of the Ozark Mountain Daredevils
Randle Cotgrave (died 1634?), English lexicographer
Randle Wilbraham Falconer (1816–1881), British medical doctor and writer
Randle Holme, the name shared by four family members who were painters and genealogists in Chester, Cheshire, England, from the late 16th to early 18th centuries
Fictional characters:
Randle McMurphy, protagonist of Ken Kesey's novel One Flew Over the Cuckoo's Nest and its film adaptation