Rahul Sharma (Editor)

RTI 120

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CAS Number
  
146145-20-2

ChemSpider
  
34948082

3D model (Jmol)
  
Interactive image

PubChem CID
  
10109793

Formula
  
C22H25NO2

Molar mass
  
335.189 g/mol

RTI-120 httpsuploadwikimediaorgwikipediacommonsthu

(–)-2β-Carbophenoxy-3β-(p-tolyl)tropane (RTI-4229-120) is a phenyltropane derivative which acts as a reasonably selective dopamine reuptake inhibitor, along with weaker inhibition of noradrenaline and serotonin reuptake. It has a reasonably fast rate of occupancy of dopamine transporters in the brain, though slower than that of cocaine itself. RTI-120 has a short duration of action, along with other p-methyl substituted phenyltropanes such as RTI-150, RTI-171 and RTI-199, giving it a more similar pharmacological profile to cocaine compared to longer acting analogues like RTI-121 and RTI-177.

References

RTI-120 Wikipedia