Species Human Entrez 340419 | Human Mouse Ensembl ENSG00000147655 | |
Aliases RSPO2, CRISTIN2, R-spondin 2 External IDs MGI: 1922667 HomoloGene: 18235 GeneCards: RSPO2 | ||
R-spondin 2 also known as roof plate-specific spondin-2 is a protein that in humans that is encoded by the RSPO2 gene.
R-spondin 2 synergizes with Wnt to activate beta-catenin. RSPO2 has been proposed to regulate craniofacial patterning and morphogenesis within pharyngeal arch 1 through ectoderm-mesenchyme signaling via the endothelin-Dlx5/6 pathway.
In dogs, the Rspo2 gene determines hair growth.
References
RSPO2 Wikipedia(Text) CC BY-SA