EC number 2.1.1.52 ExPASy NiceZyme view | CAS number 50812-26-5 | |
In enzymology, a rRNA (guanine-N2-)-methyltransferase (EC 2.1.1.52) is an enzyme that catalyzes the chemical reaction
Thus, the two substrates of this enzyme are S-adenosyl methionine and rRNA, whereas its two products are S-adenosylhomocysteine and rRNA containing N2-methylguanine.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:rRNA (guanine-N2-)-methyltransferase. Other names in common use include ribosomal ribonucleate guanine-2-methyltransferase, and S-adenosyl-L-methionine:rRNA (guanine-2-N-)-methyltransferase.
Structural studies
As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 2PJD.