Species Human Entrez 79871 | Human Mouse Ensembl ENSG00000122484 | |
Aliases RPAP2, C1orf82, Rtr1, RNA polymerase II associated protein 2 External IDs MGI: 2141142 HomoloGene: 11733 GeneCards: RPAP2 | ||
RNA polymerase II associated protein 2, also known as RPAP2, is a human gene.
Model organisms
Model organisms have been used in the study of RPAP2 function. A conditional knockout mouse line, called Rpap2tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists.
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty five tests were carried out on mutant mice and two significant abnormalities were observed. No homozygous mutant embryos were identified during gestation, and therefore none survived until weaning. The remaining tests were carried out on heterozygous mutant adult mice; no additional significant abnormalities were observed in these animals.