EC number 2.7.7.52 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 78519-53-6 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a RNA uridylyltransferase (EC 2.7.7.52) is an enzyme that catalyzes the chemical reaction
UTP + RNAnThus, the two substrates of this enzyme are UTP and RNAn, whereas its two products are diphosphate and RNAn+1.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:RNA uridylyltransferase. Other names in common use include terminal uridylyltransferase, and TUT.
Structural studies
As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 2E5G, 2IKF, 2NOM, 2Q0C, 2Q0D, 2Q0E, 2Q0F, and 2Q0G.
References
RNA uridylyltransferase Wikipedia(Text) CC BY-SA