EC number 2.7.10.2 | Entrez 8767 | |
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Aliases RIPK2, CARD3, CARDIAK, CCK, GIG30, RICK, RIP2, receptor interacting serine/threonine kinase 2 External IDs MGI: 1891456 HomoloGene: 37856 GeneCards: RIPK2 |
Receptor-interacting serine/threonine-protein kinase 2 is an enzyme that in humans is encoded by the RIPK2 gene.
This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-κB and inducer of apoptosis in response to various stimuli.
Interactions
RIPK2 has been shown to interact with BIRC2.{
References
RIPK2 Wikipedia(Text) CC BY-SA