Species Human Entrez 8601 | Human Mouse Ensembl ENSG00000147509 | |
 | ||
Aliases RGS20, RGSZ1, ZGAP1, g(z)GAP, gz-GAP, regulator of G-protein signaling 20 External IDs MGI: 1929866 HomoloGene: 2745 GeneCards: RGS20 | ||
Regulator of G-protein signaling 20 is a protein that in humans is encoded by the RGS20 gene.
Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.[supplied by OMIM]
In melanocytic cells RGS20 gene expression may be regulated by MITF.
Interactions
RGS20 has been shown to interact with GNAO1 and GNAZ.
References
RGS20 Wikipedia(Text) CC BY-SA