Retinol dehydrogenase 16 (all-trans) is a protein that in humans is encoded by the RDH16 gene. The gene is also known as RODH-4 and SDR9C8.
Model organisms
Model organisms have been used in the study of RDH16 function. A conditional knockout mouse line, called Rdh16tm1a(KOMP)Wtsi was generated as part of the International Knockout Mouse Consortium program — a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists — at the Wellcome Trust Sanger Institute.
Male and female animals underwent a standardized phenotypic screen to determine the effects of deletion. Twenty four tests were carried out on mutant mice, but no significant abnormalities were observed.
References
RDH16 Wikipedia(Text) CC BY-SA