Species Human Entrez 149041 | Human Mouse Ensembl ENSG00000135870 | |
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Aliases RC3H1, RNF198, ROQUIN, ring finger and CCCH-type domains 1 External IDs MGI: 2685397 HomoloGene: 19036 GeneCards: RC3H1 | ||
Ring finger and CCCH-type domains 1, also known as Roquin-1, is a protein that in humans is encoded by the RC3H1 gene.
Function
This gene encodes a protein containing RING-type and C3H1-type zinc finger motifs. The encoded protein recognizes and binds to a constitutive decay element (CDE) in the 3' UTR of mRNAs, leading to mRNA deadenylation and degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
References
RC3H1 Wikipedia(Text) CC BY-SA