Quine is a Manx surname. Notable people with the surname include:
Edgar Quine (born 1934), Manx politician
John Quine (1857-1940), Manx clergyman, scholar and writer - author of The Captain of the Parish
Richard Quine (1920–1989), American stage, film, and radio actor and film director
Robert Quine (1942–2004), American guitarist
Willard Van Orman Quine (1908–2000), American analytic philosopher and logician
William Edward Quine (1847–1922), Manx American physician and academic
