Species Human Entrez 9444 | Human Mouse Ensembl ENSG00000112531 | |
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Aliases QKI, Hqk, QK, QK1, QK3, hqkI, KH domain containing, RNA binding External IDs MGI: 97837 HomoloGene: 11059 GeneCards: QKI | ||
Quaking homolog, KH domain RNA binding (mouse), also known as QKI, is a protein which in humans is encoded by the QKI gene.
QKI belongs to a family of RNA-binding proteins called STAR proteins for Signal Transduction and Activation of RNA. They have an HNRNPK homology (KH) domain embedded in a 200-amino acid region called the GSG domain. Other members of this family include SAM68 (KHDRBS1) and SF1 . Two more new members are KHDRBS3 and KHDRBS2.
The QKI gene is implicated as being important in schizophrenia, and QKI controls translation of many oligodendrocyte-related genes.
References
QKI Wikipedia(Text) CC BY-SA