EC number 6.1.1.26 | ExPASy NiceZyme view MetaCyc | |
Pyrrolysine—tRNAPyl ligase (EC 6.1.1.26, PylS, pyrrolysyl-tRNA synthetase) is an enzyme with systematic name L-pyrrolysine:tRNAPyl ligase (AMP-forming). This enzyme catalyses the following chemical reaction
ATP + L-pyrrolysine + tRNAPyl
This enzyme is specific for pyrrolysine as substrate as it cannot be replaced by lysine or any of the other natural amino acids.
References
Pyrrolysine—tRNAPyl ligase Wikipedia(Text) CC BY-SA