EC number 3.4.19.6 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 60063-88-9 BRENDA BRENDA entry KEGG KEGG entry | |
Pyroglutamyl-peptidase II (EC 3.4.19.6, thyroliberinase, pyroglutamyl aminopeptidase II, thyrotropin-releasing factor pyroglutamate aminopeptidase, pyroglutamate aminopeptidase II, pyroglutamyl peptidase II, thyroliberin-hydrolyzing pyroglutamate aminopeptidase, thyrotropin-releasing hormone-degrading pyroglutamate aminopeptidase, thyrotropin-releasing hormone-degrading peptidase, TRH aminopeptidase) is an enzyme. This enzyme catalyses the following chemical reaction
Release of the N-terminal pyroglutamyl group from pGlu--His-Xaa tripeptides and pGlu--His-Xaa-Gly tetrapeptidesThis enzyme is highly specific for thyrotropin releasing hormone.
References
Pyroglutamyl-peptidase II Wikipedia(Text) CC BY-SA