EC number 1.97.1.2 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 125978-84-9 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a pyrogallol hydroxytransferase (EC 1.97.1.2) is an enzyme that catalyzes the chemical reaction
1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzeneThus, the two substrates of this enzyme are 1,2,3,5-tetrahydroxybenzene and 1,2,3-trihydroxybenzene (pyrogallol), whereas its two products are 1,3,5-trihydroxybenzene (phloroglucinol) and 1,2,3,5-tetrahydroxybenzene.
This enzyme belongs to the family of oxidoreductases. The systematic name of this enzyme class is 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxytransferase. Other names in common use include 1,2,3,5-tetrahydroxybenzene hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:pyrogallol transhydroxylase, 1,2,3,5-tetrahydroxybenzene-pyrogallol hydroxyltransferase (transhydroxylase), pyrogallol hydroxyltransferase, 1,2,3,5-tetrahydroxybenzene:1,2,3-trihydroxybenzene hydroxyltransferase. This enzyme participates in benzoic acid degradation via CoA ligation.
Structural studies
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1TI2, 1TI4, 1TI6, 1VLD, 1VLE, and 1VLF.