EC number 1.5.4.1 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 93586-06-2 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a pyrimidodiazepine synthase (EC 1.5.4.1) is an enzyme that catalyzes the chemical reaction
a pyrimidodiazepine + glutathione disulfide + H2OThe 3 substrates of this enzyme are pyrimidodiazepine, glutathione disulfide, and H2O, whereas its two products are 6-pyruvoyltetrahydropterin and glutathione.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH group of donors with a disulfide as acceptor. The systematic name of this enzyme class is pyrimidodiazepine:glutathione-disulfide oxidoreductase (ring-opening, cyclizing). Other names in common use include PDA synthase, pyrimidodiazepine:oxidized-glutathione oxidoreductase (ring-opening,, and cyclizing). This enzyme participates in glutathione metabolism.
References
Pyrimidodiazepine synthase Wikipedia(Text) CC BY-SA