Samiksha Jaiswal (Editor)

Pyrimidine oxygenase

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EC number
  
1.14.99.46

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

Pyrimidine oxygenase (EC 1.14.99.46, RutA) is an enzyme with systematic name uracil,FMNH2:oxygen oxidoreductase (uracil hydroxylating, ring-opening) . This enzyme catalyses the following chemical reaction

(1) uracil + FMNH2 + O2 (Z)-3-ureidoacrylate peracid + FMN (2) thymine + FMNH2 + O2 (Z)-2-methylureidoacrylate peracid + FMN

In vitro the product (Z)-3-ureidoacrylate peracid is spontaneously reduced to ureidoacrylate.

References

Pyrimidine oxygenase Wikipedia