Harman Patil (Editor)

Pyridoxine 5' phosphate synthase

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EC number
  
2.6.99.2

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

MetaCyc
  
metabolic pathway

In enzymology, a pyridoxine 5'-phosphate synthase (EC 2.6.99.2) is an enzyme that catalyzes the chemical reaction

Contents

1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate pyridoxine 5'-phosphate + phosphate + 2 H2O

Thus, the two substrates of this enzyme are 1-deoxy-D-xylulose 5-phosphate and 3-amino-2-oxopropyl phosphate, whereas its 3 products are pyridoxine 5'-phosphate, phosphate, and H2O.

Classification

This enzyme belongs to the family of transferases, specifically those transferring nitrogenous groups transferring other nitrogenous groups.

Nomenclature

The systematic name of this enzyme class is 1-deoxy-D-xylulose-5-phosphate:3-amino-2-oxopropyl phosphate 3-amino-2-oxopropyltransferase (phosphate-hydrolysing; cyclizing). Other names in common use include pyridoxine 5-phosphate phospho lyase, PNP synthase, and PdxJ.

Biological role

This enzyme participates in vitamin B6 metabolism.

References

Pyridoxine 5'-phosphate synthase Wikipedia