Pyridoxal 4 dehydrogenase

In enzymology, a pyridoxal 4-dehydrogenase (EC 1.1.1.107) is an enzyme that catalyzes the chemical reaction

Thus, the two substrates of this enzyme are pyridoxal and NAD⁺, whereas its 3 products are 4-pyridoxolactone, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is pyridoxal:NAD⁺ 4-oxidoreductase. This enzyme is also called pyridoxal dehydrogenase. This enzyme participates in vitamin B₆ metabolism.