Neha Patil (Editor)

Pyranose oxidase

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EC number
  
1.1.3.10

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
37250-80-9

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

Pyranose oxidase

In enzymology, a pyranose oxidase (EC 1.1.3.10) is an enzyme that catalyzes the chemical reaction

D-glucose + O2 2-dehydro-D-glucose + H2O2

Thus, the two substrates of this enzyme are D-glucose and O2, whereas its two products are 2-dehydro-D-glucose and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is pyranose:oxygen 2-oxidoreductase. Other names in common use include glucose 2-oxidase, and pyranose-2-oxidase. This enzyme participates in pentose phosphate pathway. It employs one cofactor, FAD.

Structural studies

As of late 2007, 8 structures have been solved for this class of enzymes, with PDB accession codes 1TT0, 1TZL, 2F5V, 2F6C, 2IGK, 2IGM, 2IGN, and 2IGO.

References

Pyranose oxidase Wikipedia