Putative actinobacterial holin X family

The putative actinobacterial holin-X (Hol-X) family (TC# 1.E.34) was retrieved as a distant member of TC family 1.E.20, suggesting membership of the holin superfamily III. Most Hol-X proteins are less than 200 amino acyl residues (aas) in length and possess two transmembrane segments (TMSs). Structural analysis has been done computationally since, as of early 2016, crystal structural data are not available for members of this family. These proteins have not been functionally characterized. A representative list of proteins belonging to this family can be found in the Transporter Classification Database.