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Psi DOM

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CAS Number
  
80888-36-4

ChEMBL
  
CHEMBL293399

3D model (Jmol)
  
Interactive image

ChemSpider
  
21106372

Formula
  
C12H19NO2

Molar mass
  
209.29 g/mol

Psi-DOM

Legal status
  
US: Analogue to a Schedule I/II drug (but only if it is intended for human consumption)

Ψ-DOM, or 2,6-dimethoxy-4-methylamphetamine, is a hallucinogenic, psychedelic drug and a structural isomer of the better-known hallucinogen DOM. Ψ-DOM was first reported by Alexander Shulgin in his book PiHKAL (Phenethylamines i Have Known And Loved).

Ψ-DOM has similar effects to DOM, but is only around 1/3 - 1/2 the potency, with an active dose reported to be between 15-25 milligrams. The effects of Ψ-DOM last for around 6–8 hours.

The activity of Ψ-DOM (and Ψ-2C-T-4) demonstrates that the two methoxy groups on the psychedelic phenethylamines are not strictly limited to the 2,5 positions on the phenyl ring. Indeed any of the 2Cx or DOx series of drugs could alternatively be made as the 2,6 isomer and would still be expected to show similar activity, although slightly less potent. In theory this would vastly expand the range of different hallucinogens that could be derived from this family of drugs. The 2,6 isomer of another similar drug 2C-D-FLY (see 2C-B-FLY) has also been made by David E. Nichols and found to be active, this might by extension be referred to as Ψ-2C-D-FLY.

References

Psi-DOM Wikipedia