Protoporphyrinogen IX dehydrogenase (menaquinone)

Updated on Dec 26, 2024

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EC number 1.3.5.3 BRENDA BRENDA entry KEGG KEGG entry		IntEnz IntEnz view ExPASy NiceZyme view MetaCyc metabolic pathway

Protoporphyrinogen IX dehydrogenase (menaquinone) (EC 1.3.5.3, HemG) is an enzyme with systematic name protoporphyrinogen IX:menaquinone oxidoreductase. This enzyme catalyses the following chemical reaction

protoporphyrinogen IX + 3 menaquinone ⇌ protoporphyrin IX + 3 menaquinol

This enzyme enables Escherichia coli to synthesize heme in both aerobic and anaerobic environments.

References

Protoporphyrinogen IX dehydrogenase (menaquinone) Wikipedia

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