EC number 4.2.1.28 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 9026-90-8 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, a propanediol dehydratase (EC 4.2.1.28) is an enzyme that catalyzes the chemical reaction
propane-1,2-diolHence, this enzyme has one substrate, 1,2-propanediol, and two products, propanal and H2O.
This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is propane-1,2-diol hydro-lyase (propanal-forming). Other names in common use include meso-2,3-butanediol dehydrase, diol dehydratase, DL-1,2-propanediol hydro-lyase, diol dehydrase, adenosylcobalamin-dependent diol dehydratase, propanediol dehydrase, coenzyme B12-dependent diol dehydrase, 1,2-propanediol dehydratase, dioldehydratase, and propane-1,2-diol hydro-lyase. This enzyme participates in glycerolipid metabolism. It employs one cofactor, cobamide.
Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1DIO, 1EEX, 1EGM, 1EGV, 1IWB, 1UC4, and 1UC5.