Formula C39H54N10O11S Appearance Colorless, odorless | Molar mass 870.97 g/mol | |
 | ||
Promanullin is a cyclic nonribosomal peptide. It is an amatoxin, all of which are found in several members of the Amanita genus of mushrooms.
Toxicology
Like other amatoxins, proamanullin is an inhibitor of RNA polymerase II. Promanullin has a specific attraction to the enzyme RNA polymerase II. Upon ingestion, it binds to the RNA polymerase II enzyme, effectively causing cytolysis of hepatocytes (liver cells).
References
Proamanullin Wikipedia(Text) CC BY-SA