Prepilin peptidase

Prepilin peptidase (EC 3.4.23.43) is an enzyme. This enzyme catalyses the following chemical reaction

Typically cleaves a -Gly-Phe- bond to release an N-terminal, basic peptide of 5-8 residues from type IV prepilin, and then N-methylates the new N-terminal amino group, the methyl donor being S-adenosyl-L-methionine

This enzyme is present on the surface of many species of bacteria.